Certification and Registration
Dermatest® Microbiome-friendly Seal
Category:
Dermatest
Founded in 1978, German Dermatest® is an internationally renowned, independent dermatological testing organization. Its core mission is to ensure the safety, compatibility, and efficacy of products for the skin. To this end, Dermatest® has established multiple testing and certification marks.
Microbiota microbiome
The skin harbors a complex microbial community, including bacteria and viruses. and fungi, which play a crucial role in the skin’s protective functions. These microorganisms and their surrounding environment are referred to as Microbiota microbiome 。
Natural microbial communities prevent pathogenic organisms from colonizing the skin. When the balance between commensal microbes and pathogens is disrupted, it can lead to skin diseases and even systemic illnesses.
Although the microbiota is considered relatively stable, the skin remains subject to… The influence of numerous internal and external factors. Some… Cosmetics and cleaning products It can also affect the microbiome. Therefore, ensuring the product’s microbiome‑friendly properties… Sexuality is becoming increasingly important to both consumers and manufacturers.
Dermatest® Microbiome‑Friendly Seal
Dermatest® is dedicated to conducting microbiome‑friendly testing and analysis for products that come into frequent contact with the skin. The Dermatest® Microbiome‑Friendly certification seal can be obtained upon request from the institute's microbiome team.
Microbiome-friendly products
Almost all products that come into direct contact with the skin can potentially disrupt the skin’s microbial balance; therefore, their skin‑friendliness should be assessed through microbiome testing. , thereby preserving the diversity and stability of the skin’s natural microbiota. It mainly includes various beauty products such as creams, lotions, and moisturizing creams, as well as diapers. , special attention should be paid to the following categories of products:
◎ Products for specific skin concerns: Products intended to alleviate psoriasis, rosacea, and atopic dermatitis should be rigorously evaluated for their positive effects on the microbiome.
◎ Scalp care products: For seborrheic dermatitis and dandruff, it is essential to specifically assess their impact on the fungal microbiota.
◎ Microecological Regulation Products: Contains probiotics Products containing ingredients such as prebiotics and postbiotics must be thoroughly investigated for their regulatory effects on the skin microbiome.
Microbiologically Friendly Product Testing
16S rRNA The gene is used in microbiome research due to its high conservation across bacterial species. However, in addition to highly conserved regions, the 16S rRNA gene sequence also contains hypervariable regions that provide species-specific signature sequences, facilitating bacterial identification. Similarly, the internal transcribed spacer (ITS) region can be employed for taxonomic analysis of fungi. The specific testing procedure is as follows:
Microbial Sample Collection: Microbial samples were collected from 20 volunteers at two time points: before and after product use.
DNA Extraction and Amplification: Bacterial DNA was extracted, and the 16S rRNA gene sequences were amplified; these sequences encompassed the V1 to V9 regions.
High-throughput gene sequencing: High-throughput sequencing of the 16S rRNA gene was performed to generate sequence data.
Data Processing and Analysis: Data processing, quality control, and analysis were performed using bioinformatics tools, yielding the relative abundance of bacteria and the diversity of microbial communities.
Results Interpretation: The analysis results show that micro The relative abundance and diversity of microbial communities were assessed to determine the product’s impact on the microbiota.
Procedure Of Dermatest® Microbiome‑Friendly Certification Seal
Submit an application: After submitting the certification application, provide product information and documentation, and confirm that the product will be used in bio‑group testing and applied research.
Product Evaluation: Assess the number of samples and information required for microbiome testing of the product, and conduct an internal risk analysis.
Applied Research: Conduct applied research to analyze the skin microbiome of participants before and after use.
Obtain the seal: The results of the microbiome analysis will be evaluated using bioinformatics, and upon successful completion, you will receive a report on the microbiome-friendly properties. Report on the Microbiome-Friendly Seal.
SATISFY offer a one‑stop German Dermatest certification service, including risk analysis, safety assessments, certification study protocols, and guidelines for using certification seals. For more details, please contact SATISFY customer service.
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